Matthew Heintzelman
Biology Department
Contact Information
Biology Building 205
mheintze@bucknell.edu
570-577-1209
Educational Background
A.B., Dartmouth College
M.S., Yale University
M.Phil., Yale University
Ph.D., Yale University
Teaching Interests
Biol. 205, Introduction to Molecules and Cells
Biol. 323, Microanatomy
Biol. 352, Cell Biology Research Interests
My lab studies the cytoskeleton of Gregarina polymorpha, a huge protozoan parasite that infests the gut of the mealworm Tenebrio molitor. Gregarines have a distinctive morphology and an equally distinctive mechanism of rapid cell locomotion termed gliding motility. Using a range of cell biological and molecular techniques, we seek to characterize and understand the role of the cytoskeleton (actin, myosin, microtubules) in both the organization of cell architecture and in powering the gliding motility of these unique parasites. Selected Publications
Heintzelman, M.B. (2004) Actin and myosin in Gregarina polymorpha. Cell Motil.Cytoskel. 58:83-95. Heintzelman, M.B. (2003) Gliding motility: the molecules behind the motion. Curr. Biol. 13:R57-R59. Heintzelman, M.B. and Schwartzman, J.D. (2001) Myosin diversity in Apicomplexa. J. Parasitology. 87:429-432. Heintzelman, M.B. and Schwartzman, J.D. (1999) Characterization of Myosin-A and Myosin-C: Two class XIV unconventional myosins from Toxoplasma gondii. Cell Motil. Cytoskel. 44:58-67. Heintzelman, M.B. and Schwartzman, J.D. (1997) A novel class of unconventional myosins from Toxoplasma gondii. J. Mol. Biol. 271:139-146.
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