Kenneth Field

Biology Department

Biology Building 203A
ken.field@bucknell.edu
570-577-3814

Links

Ken Field's lab page

Educational Background

B.S., University of Vermont
Ph.D., Cornell University

Teaching Interests

Immunology, Biology for non-science majors, Cell Biology

Research Interests

Farnesyltransferase inhibitor effects on lymphoid cancers and immune function.

Recent Activities

*Denotes Student

Experimental Biology Meeting, 2008. A. Gaylo*, E. J. Batzel*, K. S. Laux*, and K. A. Field “Farnesyl transferase inhibitors delay primary skin allograft rejection in class II MHC-mismatched mice,”

FASEB Summer Conference on Protein Lipidation, Signaling and Membrane Domains, 2006. K. S. Laux* and K. A. Field “The L-744,832 Farnesyl Transferase Inhibitor Delays Skin Allograft Rejection in Mice,”

American Association of Immunologists Annual Meeting, 2006. K. S. Laux*, K. M. Stoyanoff*, Y. Refaeli, and K. A. Field “Skin allograft rejection in mice is delayed by the farnesyl transferase inhibitor, L-744,832,”

Session Chair, FASEB Summer Conference on Protein Lipidation, Signaling and Membrane Domains, 2004.

American Society of Cell Biology Annual Meeting, 2003. "Effects of farnesyl transferase inhibitors on a novel mouse model of Burkitt’s lymphoma," Soratree Charoenthongtrakul*, Yosef Refaeli, J. Michael Bishop, and Ken A. Field.

American Society of Cell Biology Annual Meeting, 2003. "Effects of farnesyl transferase inhibitors on human Burkitt’s lymphoma cell lines," Erin P. O’Keefe*, Jeremiah M. Draper*, Yosef Refaeli, J. Michael Bishop, and Ken A. Field.

Damon Runyon-Walter Winchell Postdoctoral Research Fellow, J. Michael Bishop, Advisor, G. W. Hooper Foundation, University of California San Francisco.

Selected Publications

*Denotes Bucknell Student Author

Field, K.A., S. Charoenthongtrakul*, J. M. Bishop, and Y. Refaeli. 2008. Farnesyl transferase inhibitors induce extended remissions in transgenic mice with mature B cell lymphomas. Molecular Cancer 7:39.

Refaeli, Y., R. M. Young, B. C. Turner, J. Duda, K. A. Field, and J. M. Bishop. 2008. “The B-cell antigen receptor and overexpression of MYC can cooperate in the genesis of B-cell lymphomas,” PLoS Biology in press.

Refaeli, Y., K. A. Field, B. C. Turner, A. Trumpp, and J. M. Bishop. 2005. The proto-oncogene MYC can break B cell tolerance. Proc. Natl. Acad. Sci. USA. 102:4097-4102.

Field, K.A., D. Holowka, B. Baird. 1999. Structural aspects of the association of FcEpsilonRI with detergent-resistant membranes. J. Biol. Chem. 274:1753-1758.

Field, K.A., D. Holowka, and B. Baird. 1997. Compartmentalized activation of the high affinity immunoglobulin E receptor within membrane domains. J. Biol. Chem. 272:4276-4280.

Field, K.A., D. Holowka, B. Baird. 1995. Fc-epsilon-RI-mediated recruitment of p53/56-lyn to detergent-resistant membrane domains accompanies cellular signaling. Proceedings of the National Academy of Sciences, U.S.A. 92 (20): 9201-9205.