(on leave 2017-19)
- Postdoctoral fellow, University of Washington, Seattle
- Ph.D. in Biological Sciences, Stanford University
- B.S. in Molecular Biology, University of California, San Diego
- B.A. in Philosophy, University of California, San Diego
- BIOL 205 Introduction to Molecules and Cells
- BIOL 207 Genetics
- BIOL 327 Molecular Biology
- BIOL 332 Developmental Neurobiology
- BIOL 340 Biochemical Methods
I use the model organism Drosophila melanogaster to study fundamental problems in nervous system development. How do newly born cells know what types of neurons they're supposed to be? How does a neural stem cell produce distinct types of neurons at the right time during development? How do insect nervous systems reorganize during metamorphosis to accommodate radical transformations in body plan from limbless larvae to adults designed for mating and dispersal? And how have nervous systems evolved variations on the basic arthropod model to enable novel brain functions or dramatic differences in appendage type and number?
Marin, E.C., Pop S., Davey, K., and Williams, D.W. "Modification of neural circuits by developmentally regulated apoptosis in Drosophila melanogaster." Building the Brain: from Genes to Circuits and Cognition Conference, Royal Society, London, UK 2015.
Marin, E.C. "De-repression of target genes permits pruning of persistent neurons in the Drosophila mushroom body." Ecdysone Workshop, 56th Annual Drosophila Research Conference, Chicago, IL. 2015. Talk.
Lee, K.**, Wachter, R.**, Windham, A.**, Dincer, A.**, Dunne, C.**, Gordon-Hamm, D.**, and Marin, E. "Ecdysone receptor and ultraspiracle mediate activation and repression in mushroom body neuron pruning." 56th Annual Drosophila Research Conference, Chicago, IL. 2015. Poster.
Bell, K.**, Murphy, C.**, Patterson, A.**, Freehling, G.**, Panzarino, A.**, Schuler, E.**, and Marin, E. "Antp controls the differential survival and morphology of adult-specific neurons in the thoracic vs. subesophageal ganglia." 56th Annual Drosophila Research Conference, Chicago, IL. 2015. Poster.
Dunne C.R.**, Cillo A.R.**, Glick D.R.**, John K.**, Johnson C.**, Kanwal J.**, Malik B.T.**, Mammano K.**, Petrovic S.**, Pfister W.**, Rascoe A.S.**, Schrom D.**, Shapiro S.**, Simkins J.W.**, Strauss D.**, Talai R.**, Tomtishen J.P. III**, Vargas J.**, Veloz T.**, Vogler T.O.**, Clenshaw M.E.**, Gordon-Hamm D.T.**, Lee K.L.**, Marin E.C. (2014). "Structured Inquiry-Based Learning: Drosophila GAL4 Enhancer Trap Characterization in an Undergraduate Laboratory Course." PLoS Biol. Dec 30;12(12):e1002030.
Lin S.*, Marin E.C.*, Yang C.P.*, Kao C.F., Apenteng B.A., Huang Y., O'Connor M.B., Truman J.W., Lee T. (2013). "Extremes of lineage plasticity in the Drosophila brain." Curr Biol. Oct 7;23(19):1908-13.
Marin, E.C. , Dry, K.E.**, Alaimo, D.R.**, Rudd, K.T.**, Cillo, A.R.**, Clenshaw, M.E.**, Negre, N., White, K.P., and Truman, J.W. (2012). "Ultrabithorax confers spatial identity in a context-specific manner in the Drosophila postembryonic ventral nervous system." Neural Development 7:31.
Truman, J.W., Moats, W., Altman, J., Marin, E.C., and Williams, D.W. (2010). "Role of Notch signaling in establishing the hemilineages of secondary neurons in Drosophila melanogaster." Development, 137(1): 53-61.
Jefferis, G.S.X.E.*, Potter, C.J.*, Chan, A.M., Marin, E.C., Rohlfing, T., Maurer, C.R. Jr., and Luo, L. (2007). “Comprehensive maps of Drosophila higher olfactory centers: spatially segregated fruit and pheromone representation.” Cell, 128(6): 1187-203.
Ramaekers, A., Magnenat, E., Marin, E.C., Gendre, N., Jefferis, G.S.X.E., Luo, L., and Stocker, R.F. (2005). “Glomerular maps without cellular redundancy at successive levels of the Drosophila larval olfactory circuit.” Current Biology, 15: 1-11.
Marin, E.C., Watts, R.J., Tanaka, N.K., Ito, K., and Luo, L. (2005). “Developmentally programmed remodeling of the Drosophila olfactory circuit.” Development, 132(4): 725-737.
Marin, E.C.*, Jefferis, G.S.X.E.*, Komiyama, T., Zhu, H., and Luo, L. (2002). “Representation of the glomerular olfactory map in the Drosophila brain.” Cell, 109(2): 243-255.
Jefferis, G.S.X.E.*, Marin, E.C.*, Stocker, R.F., and Luo, L. (2001). “Target neuron prespecification in the olfactory map of Drosophila.” Nature, 414: 204-208.
Sturtevant, M.A., Biehs, B., Marin, E., and Bier, E. (1997). “The spalt gene links the A/P compartment boundary to a linear adult structure in the Drosophila wing.” Development, 124(1): 21-32.
*These authors contributed equally to this work.
** denotes Bucknell student co-authors