The addition of a heteroatom containing group to an olefin or alkyne is one of the most powerful ways to prepare complex organic compounds containing nitrogen, phosphorus, or sulfur containing groups. Hydroelementation reactions and Michael additions are examples of processes that efficiently generate these functionalized compounds through the formation of new carbon-heteroelement bonds.
Microwave assisted synthesis has had a dramatic effect on how synthetic chemists approach the preparation of new compounds. Rapid reaction rates, ultralow catalyst loadings, and the minimization of secondary reactions are only some of the benefits of microwave assisted chemistry. The blending of microwave assisted chemistry with carbon heteroatom bond forming reactions facilitates the generation of new and intriguing compounds. One aspect of our research program is focused on the synthesis of new organic compounds through the design and development of new microwave assisted transformations.
Some of our recent developments are shown below (undergraduates in bold):
R. I. Taylor, L. E. Thompson, P. B. Patel, and R. A. Stockland Jr. Org. Lett. 2005, 7, 851.
G. F. Manbeck, A. J. Lipman, R. A. Stockland Jr., A. L. Freidl, A. F. Hasler, J. J. Stone, and I. A. Guzei J. Org. Chem. 2005, 70, 244. - highlighted on www.organic-chemistry.org
A. J. Lipman, J. A. Bawiec, P. E. Morrison, I. A. Guzei, P. M. Findeis, J. F. Tamblin. and R. A. Stockland Jr.J. Organomet. Chem. 2006, 691, 4042.
Robert A. Stockland Jr.
Professor of Chemistry
312 Rooke Chemistry Bldg