James Baish

Education

• B.S.M.E., Bucknell University, 1979
• M.S.E., University of Pennsylvania, 1983
• Ph.D., University of Pennsylvania, 1986

Faculty Research Interests

• Biomedical heat and mass transfer
• Biomedical fluid mechanics
• Cancer physiology 
• Lymphatic physiology

Recent Courses Taught

• Biotransport I (BMEG 300)
• Biotransport II (BMEG 400)
• Biomedical Signals and Systems (BMEG 350)
• Biomedical Imaging (BMEG 463)
• Engineering Design Experience (ENGR 100)

Awards and Honors

• 1956 Lectureship for Inspirational Teaching
• Presidential Professor (2007-2010)
• Fellow ASME
• NSF Presidential Young Investigator

Recent and Representative Publications

Bicuspid valve closure and backflow prevention: Role of leaflet geometry, B. Kauoi, A. Bou Orm, P. Navet, J. Baish, L. L. Munn, Physical Review Fluids 11:033103 2026; DOI: https://doi.org/10.1103/bxwj-qlxf

Macrophages recruited by implanted fibrin gels promote regeneration of injured lymphatic vessels, Mohammad S Razavi, Pin-Ji Lei, Zohreh Amoozgar, Nichaluk Leartprapun, Seemantini K Nadkarni, James W Baish, Timothy P Padera, Lance L Munn, Scientific Reports 2026, https://doi.org/10.1038/s41598-026-39167-2

Overcoming impaired dendritic cell antigen presentation in tumor draining lymph nodes facilitates immunotherapy responses, Meghan J. O’Melia, Pin-ji Lei, Neian Contreras-Alvarado, Lutz Menzel, Johanna J. Rajotte, Mohammad R. Nikmaneshi, James W. Baish, Jessalyn M. Ubellacker, Genevieve M. Boland, Sonia Cohen, Lance L. Munn, Timothy P. Padera, Journal for ImmunoTherapy of Cancer 2025;13:e013364. doi:10.1136/jitc-2025-013364

Aging-induced changes in lymphatic muscle cell transcriptomes are associated with reduced pumping of peripheral collecting lymphatic vessels in mice, Pin-Ji Lei, Katarina J. Ruscic, Kangsan Roh, Johanna J. Rajotte, Meghan J. O’Melia, Echoe M. Bouta, Marla Marquez, Ethel R. Pereira, Ashwin S. Kumar, Mohammad S. Razavi, Hengbo Zhou, Lutz Menzel, Liqing Huang, Heena Kumra, Mark Duquette, Peigen Huang, James W. Baish, Lance L. Munn, Natasza A. Kurpios, Jessalyn M. Ubellacker, Timothy P. Padera, Developmental Cell http://doi.org/10.1016/j.devcel.2024.12.010 

Experimental and theoretical model of microvascular network remodeling and blood flow redistribution following minimally invasive microvessel laser ablation Gabriel Gruionu, James Baish, Sean McMahon, David Blauvelt, Lucian G. Gruionu, Mara Onita Lenco, Benjamin J. Vakoc, Timothy P. Padera, Lance L. Munn, Scientific Reports, 2024, 14:8767,| https://doi.org/10.1038/s41598-024-59296-w

Mathematical Model of Oxygen, Nutrient, and Drug Transport in Tuberculosis Granulomas, Meenal Datta, McCarthy Kennedy, Laura E. Via, James W. Baish , Lei Xu, Veronique Dartois, Clifton E. Barry 3 rd, and Rakesh K. Jain, PLOS Computational Biology, 2024, https://doi.org/10.1371/journal.pcbi.1011847

Fluid dynamics and leukocyte transit in the lymphatic system, Huabing Li, Jingjing Zhang, Timothy P Padera, James W Baish, Lance L Munn, PNAS Nexus, Volume 3, Issue 6, June 2024, page195, https://doi.org/10.1093/pnasnexus/pgae195

Transport barriers influence the activation of anti-tumor immunity: a systems biology analysis, Mohammad R. Nikmaneshi, James W. Baish, Timothy P. Padera, Lance Munn, Advanced Science, DOI: 10.1002/advs.202304076, 2023

Computational simulations of the effects of gravity on lymphatic transport, Huabing Li, Huajian Wei, Timothy P. Padera, James W. Baish, and Lance Munn, PNAS Nexus, Vol. 1(5), https://doi.org/10.1093/pnasnexus/pgac237, 2022

The effects of gravity and compression on interstitial fluid transport in the lower limb, James W. Baish, Timothy P. Padera, Lance L. Munn, Scientific Reports, 12:4890, 2022